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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
18.79
Human Site:
T374
Identified Species:
34.44
UniProt:
P39880
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39880
NP_853530.2
1505
164273
T374
A
P
S
E
G
A
G
T
Q
D
A
A
K
P
L
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
T385
A
P
S
E
G
A
G
T
Q
D
A
A
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
T651
A
P
S
E
G
A
G
T
Q
D
A
A
K
P
L
Dog
Lupus familis
XP_546939
1411
154543
A356
K
Y
D
E
E
I
T
A
K
A
D
E
I
E
M
Cat
Felis silvestris
Mouse
Mus musculus
P53564
1515
165577
T372
A
P
S
E
G
A
G
T
Q
D
S
T
K
P
L
Rat
Rattus norvegicus
P53565
862
92341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
S422
A
S
A
N
C
S
L
S
Q
N
I
S
K
S
E
Chicken
Gallus gallus
XP_425393
1673
183755
A519
A
P
P
E
S
S
G
A
Q
D
A
S
K
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
S328
A
S
A
N
G
S
S
S
Q
E
S
A
K
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
K653
A
L
A
A
E
A
L
K
N
G
A
S
D
A
L
Honey Bee
Apis mellifera
XP_623857
1936
209316
P519
S
Q
I
P
T
G
E
P
G
K
S
L
E
H
L
Nematode Worm
Caenorhab. elegans
Q9BL02
1273
143507
E263
R
V
S
Q
L
E
N
E
A
E
K
V
N
E
S
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
I386
S
S
S
E
G
G
S
I
S
E
K
E
D
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
83.1
56.2
N.A.
88.8
47.1
N.A.
44.3
77.4
N.A.
40.9
N.A.
23.3
23.7
22.3
29.1
Protein Similarity:
100
98.6
83.4
64.5
N.A.
91.8
50
N.A.
60
81.7
N.A.
55.4
N.A.
37.4
41
41
46.6
P-Site Identity:
100
100
100
6.6
N.A.
86.6
0
N.A.
20
66.6
N.A.
33.3
N.A.
26.6
6.6
6.6
20
P-Site Similarity:
100
100
100
20
N.A.
93.3
0
N.A.
53.3
80
N.A.
66.6
N.A.
40
26.6
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
0
24
8
0
39
0
16
8
8
39
31
0
8
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
39
8
0
16
0
0
% D
% Glu:
0
0
0
54
16
8
8
8
0
24
0
16
8
16
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
47
16
39
0
8
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
8
0
8
0
0
8
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
8
8
16
0
54
0
0
% K
% Leu:
0
8
0
0
8
0
16
0
0
0
0
8
0
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
16
0
0
8
0
8
8
0
0
8
0
0
% N
% Pro:
0
39
8
8
0
0
0
8
0
0
0
0
0
39
0
% P
% Gln:
0
8
0
8
0
0
0
0
54
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
24
47
0
8
24
16
16
8
0
24
24
0
8
8
% S
% Thr:
0
0
0
0
8
0
8
31
0
0
0
8
0
8
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _